The Current Status and Prospects of Chinese Pharmaceutical Glass Packaging (II)

Second, water injection packaging Acupuncture package is mainly glass ampoule, the current domestic market demand is 29 billion, domestic manufacturers, the pharmaceutical industry in 1990 began to eliminate non-elastic ampoule forced, but the current problem of ampoule easy to fold Outstanding. The purpose of implementing the easy-to-fold ampoule is to make the ampoule easy to fold, so as to avoid the glass particles formed by slamming from entering the solution when the ampoule is used. Studies have shown that glass particles will have serious consequences if the liquid enters the human body. In addition, the victim also has medical personnel. The incidents in which the ampoule is not easy to break due to injection are frequent occurrences, and the patient's medication safety and medical care The use of personnel brings great risks and threats.
The main reasons for the above problems are as follows: First, the level of product standards is low; second, the indicators of product quality, wall thickness and breakage force are below the requirements, and some small and medium-sized enterprises and pharmaceutical companies ignore the social benefits, ignoring the quality and use of ampoules. Security has contributed to the emergence of low-quality, low-price and competitive sales in the market.
According to market research and analysis, China's pharmaceutical injections will increase at a rate of 5% per annum. In 2010, the output will reach 37.5 billion, and 10% to 15% of the injections will require ampoules resistant to strong acids, alkalis, and light, and 5% of ampoules. Need quality printing.
Third, the infusion bottle filled with infusion of pharmaceutical packaging is still the main glass infusion bottle, the product's good air tightness, clean and transparent, non-perishable, and many other advantages make it a lot of use. However, the repeated use of glass infusion bottles has become a major problem that currently threatens people's safe use of drugs.
China's "Pharmacopoeia" requirements, for the injection of glass bottles for infusion, the water resistance of the inner surface must meet the requirements of HC1 class and HC2 class in GB12416.1 (the standard is equivalent to ISO4802), the glass that meets this requirement There are two kinds: one is borosilicate glass containing boron oxide (B2O3) 10%, referred to as I-type glass for short, and it has excellent chemical stability. Currently, there are no infusion bottles made of this glass in China, and there are not many internationally used glass infusion bottles. The other is the internal surface treatment of sodium - calcium - silicate glass, referred to as type II glass, its inner surface has a very thin layer of silicon-rich, can achieve the effect of type I glass, widely used internationally use. At present, China's 1/3 infusion bottle is made of this glass, and the remaining 2/3 infusion bottle is made of 2% non-I non-II type glass containing boron oxide (B2O3). Tests have shown that type II glass is superior to non-I and non-type II glass in water resistance, but type II glass is only desalinated on the inner surface to form a very thin silicon-rich layer and close to type I glass, such as repeated use Due to the damage during the bottle washing and filling disinfection process, the extremely thin silicon-rich layer will be destroyed and the performance will be reduced. Therefore, the national standard GB2639 clearly stipulates that Type II glass is only suitable for single-use infusion bottles.
At present, there is a big gap between the quality of domestic infusion bottles and the quality of similar products in the world. The difference is mainly in the lightness, cleanliness, transparency and uniformity of the packaging.
Fourth, the development trend of the pharmaceutical industry impact on the pharmaceutical glass packaging The pharmaceutical industry is internationally recognized as "the never-fading sunrise industry," human survival and health can not be separated from medicine. In recent years, the economy of our country's pharmaceutical industry has been very dynamic. According to the prediction of experts, by 2005, the demand for drugs in China will reach 218 billion yuan, a net increase of 94 billion yuan over 2000. The three factors that are irreversible, namely the growth of the total population, the aging of the population structure, and the flow of rural population to the cities, will be the basic conditions for the steady growth of the domestic pharmaceutical market.
During the “10th Five-Year Plan” period, China’s rural medicine market will be rapidly expanded. It is predicted that by 2010, the total rural medicine consumption will reach RMB 40 billion. There is no doubt that the vast rural medicine market will give antibiotics generic medicine. Provide huge business opportunities. The potential development space of the Chinese pharmaceutical market plays a decisive role in the development and growth of pharmaceutical glass packaging.
At present, China has become the world's second largest producer of pharmaceutical raw materials, and the output of antibiotics and vitamins is among the best in the world. China's antibiotic raw materials have been exported in large quantities. In addition, the growth in the demand for imported drugs was curbed, the import volume of pharmaceutical preparations declined, and the antibiotic imports were the most affected. Their market share has been replaced by domestic drugs and “joint ventures,” and antibiotics are widespread in developing Asian countries. The abuse of antibiotics caused by a high proportion of factors, so in the future for a long period of time, antibiotic drugs in the protagonist or general medicine, its quality and cheap, in line with the needs of more than one billion Chinese people. For glass bottles containing antibiotics, there will still be steady development. With the progress of society, the improvement of people’s living standards, and accession to the WTO, the proportion of various types of new drugs, special drugs, and high-grade and valuable drugs will gradually increase. Such drugs will raise the demand for the upgrading and upgrading of medicinal glass. Demand, this development trend can drive up the added value of medicinal glass packaging products.
Fifth, the impact of other packaging materials on pharmaceutical glass packaging In recent years, all types of packaging materials are competing with each other in the packaging field with their unique performance advantages. However, drugs are special commodities. As pharmaceutical packaging, its most important function is to ensure stable compatibility and compatibility with drugs, ie, to ensure that drugs do not deteriorate or fail due to changes in chemical properties during storage and use. Pharmaceutical glass packaging has become a preferred material for pharmaceutical packaging because of its good chemical stability, air tightness, clear, transparent, high temperature resistance, and easy sterilization. As far as antibiotic powder is concerned, other packaging materials cannot yet enter this field. The main packaging of water injections is glass ampoules. However, there are plastic ampules and injection-integrated packaging in foreign countries (ie, water-acupuncture liquids are directly encapsulated in syringes). The quality of the printing and printing of the ampoules, the brown light and the low expansion coefficient of the ampoules still have great potential for development.
More than 95% of domestic infusion preparations are glass-wrapped, but in Europe, America, and Japan, in addition to high-grade nutritional infusion bottles, conventional infusion packaging has been replaced by high-quality plastic bottles and hoses. It is expected that in the next 10 years, China's soft plastic infusion packaging will also show a steady development trend. The function of brown glass bottles for tablets has been largely replaced by plastic bottles and blister packs. Nowadays, brown glass bottles are mainly filled with all kinds of oral liquid preparations. With the improvement of people's living standards and the enhancement of protection awareness, various types of oral liquid medicines and health care products are expected to have great development potential. Brown glass bottles will occupy this market space with advantages such as smoothness, transparency, darkness, and stability.
Sixth, the impact of accession to WTO on pharmaceutical glass packaging The impact of WTO accession on pharmaceutical glass packaging can be said to be the same challenges and opportunities. The challenge is mainly reflected in the product structure and product quality. With the tremendous abundance of human material life, various new special drugs are emerging, and the demand for packaging quality will also become higher and higher. This will be a serious issue for the development of pharmaceutical glass packaging in China. However, accession to the WTO will also accelerate the pace of pharmaceutical glass packaging into the international market. Large-scale foreign products entering the Chinese market will still face barriers to price factors.
VII. Impact of pharmaceutical-related policies on pharmaceutical glass packaging The reform of the urban medical insurance system, the reform of the medical and health system, and the reform of the pharmaceutical distribution system have entered a substantive stage of operation. These reforms will have a major impact on the pharmaceutical market and will also give The closely related drug packaging brings new vitality, and the implementation of drug classification management will also bring historic changes to drug packaging. The OTC market has great potential and will be a serious issue for the development of medicinal glass packaging.
The “Measures for the Administration of Pharmaceutical Packaging Materials and Containers” promulgated by the State Drug Administration has required the registration and management of medicinal glass packaging, which can shut out a large number of small businesses and prevent the vicious competition in the industry. The packaging market will play a role.
In summary, in the face of the rapid development of the pharmaceutical industry in the 21st century, in the face of the arrival of international economic integration, in the face of various types of packaging materials that infiltrate and replace each other, pharmaceutical glass packaging in China will face a new history. Development period. We believe that through the joint efforts of people of insight from all walks of life, medicinal glass packaging will stand in the 21st century pharmaceutical packaging forest with even better performance.

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