Gu Yan reagent-Japan found that the special protein Hsp90 in the human body can promote cancer progression

Japan found that the special protein Hsp90 in the human body can promote cancer deterioration. Researchers at Gunma University in Japan published a paper recently that a special protein in the human body can promote cancer deterioration and inhibit this protein from functioning. . The researchers published a paper in the online edition of the new American "Molecular Cell" (Molecular Cell) magazine, saying that this special protein is called "Hsp90" and can enhance the function of the polymerase "Polη". "Polη" is easy to make DNA (deoxyribonucleic acid) mistakes in the replication process, resulting in genetic mutation. If the genes of cancer cells are repeatedly mutated due to "Polη", it will lead to the deterioration of cancer and the resistance of cancer cells to chemoradiation. The researchers found that if the drug was used to prevent "Hsp90" from functioning, "Polη" would be broken down or become ineffective, and the rate of cancer deterioration would be significantly slowed down. Takayama Yamashita, a professor at Gunma University who participated in the research, said that previous cancer treatments had inhibited the proliferation of cancer cells themselves. This discovery will make the inhibitory protein "Hsp90" the main direction of attack.

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